منابع مشابه
LIM Homeobox Genes and the CNS A Close Relationship
A Close Relationship protein interactions. LHX proteins have a conserved structure in which two distinct LIM domains are placed N-terminal of a centrally located DNA binding homeodomain, while the C-termi-Homeobox genes are the prototypical patterning fac-nal region contains activating, repressing, and possibly tors. There is hardly a patterning process, establishment other functional elements ...
متن کاملHomeobox Genes and the Homeobox
Most homeobox [5] genes [4] contain a 180-base-pair region called a homeodomain [6]. The homeodomain [6] portion of the protein transcript has been shown to interact with DNA in a cisregulatory fashion during the critical stages of early body plan specification and embryogenesis [7]. These sorts of interactions demonstrate the importance of regulatory genes [4] and their architectural role in t...
متن کاملExpression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta.
The LIM homeobox containing genes of the LIM-3 group, Lhx3 and Lhx4, are critical for normal development. Both genes are involved in the formation of the pituitary and the motoneuron system and loss of either gene causes perinatal lethality. Previous studies had shown that Lhx3 is overexpressed in hyperplastic placentas of mouse interspecies hybrids. To determine the role of LHX3 in the mouse p...
متن کاملExpression dynamics of the LIM-homeobox genes, Lhx1 and Lhx9, in the diencephalon during chick development.
The diencephalon is the caudal part of the developing forebrain, which corresponds to prosomeres 1 to 3. The mature diencephalon is functionally and anatomically divided into well-defined nuclei. Previous researches have shown that LIM-homeobox genes are important transcription factors during diencephalon regionalization in mice. Here we examined expression patterns of several chick orthologs o...
متن کاملHomeotic genes and the homeobox.
INTRODUCTION............................................................................... ...... 147 PHENOTYPIC EFFECTS OF HOMEOTIC MUTATIONS . .. ....... .............. .......... 149 GENETIC AND MOLECULAR ORGANIZATION ..... ............................ .......... 154 The Antennapedia Complex . . ...................................... ................ ............. 154 The Bithorax Complex ....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuron
سال: 2001
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(01)00307-5